The following webtools have been retired. Please review the replacement tools below.
As part of the dissemination goals of the national resource, we present the following software packages.
ProSight Lite is a free Windows application for matching a single candidate protein sequence and its modifications against a set of mass spectrometric observations.
NRTDP TDPortal is the front end to our search system running on high performance computing at Northwestern University.
Top Down Viewer is a free Windows application to review results from our high-throughput search system.
A free Windows application that provides a graphical interface for adding user-defined features to UniProt-formatted XML files for better informed proteoform searches.
Software for analyzing native complexes and proteins.
Deep dive software for validating your fragmentation data.
Top Down search engine now in Thermo Scientific™ Proteome Discoverer™ Software.
Complex Search Tool: A new search engine designed for hierarchical top-down analyses, identification, and scoring of whole protein complexes by native, tandem mass spectrometry is available on-line. An example of the type of results that can be used is available here. A description of this tool along with several use cases was recently published and can be found here.
External Software Libraries
As part of developing our applications, the NRTDP uses a handful of external libraries. We would like to thank the following companies for their generous academic, free-use licensing.