Current Driving Biomedical Projects

Biomedical projects drive innovation at the National Resource for Translational and Developmental Proteomics.

Below are a list of currently active projects.

 

  Identification of proteoform biomarkers in liver transplant rejection

Top and Middle Down of p53 Modification Codes

 Proteoforms in Proteinopathies

 Definition of TREG and TEFF/MEM transcriptional and proteomic profiles of liver transplant patients undergoing calcineurin inhibitors withdrawal

Histone Modifications in Acute Myeloid Leukemia

 Next-Generation Serology by Mass Spectrometry: Readout of the SARS-CoV-2 Antibody Repertoire

Individual Ion Mass Spectrometry of p53

Characterization of RAS Family Proteins in Colorectal Cancer

Proteoform Analysis in Pediatric Glioma

 Alpha-Synuclein Proteoforms in Neurodegeneration

 

 

Completed Driving Biomedical Projects

Biomedical projects drive innovation at the National Resource for Translational and Developmental Proteomics.

Below are a list of completed projects.

 

   New Interface for Faster Proteoform Analysis: Immunoprecipitation Coupled with SampleStream-Mass Spectrometry

   Apolipoprotein A proteoforms and their associations with indices of cardiometabolic health

Using Top-Down Mass Spectrometry to Detect, Quantify and Isotype Monoclonal Immunoglobulins in Serum

Tracking Allograft Outcomes Using High-throughput Whole Protein Analysis

Top-Down Proteomics of Chronic Lymphocytic Leukemia

   Histone Modification Dynamics in Heart Failure